Durysta Intracameral Implant for Glaucoma Management

The Durysta Intracameral Implant offers a revolutionary way to manage glaucoma by reducing daily eye drop reliance. Get in touch with our experienced eye doctors listed with Specialty Vision for personalized advice on this innovative treatment.

Table of Contents

Durysta: Manage Glaucoma Without Eye Drops & Who Is a Good Candidate for Durysta? & You Have Open-Angle Glaucoma or High Eye Pressure & You Respond Well to Bimatoprost Eye Drops & Your Cornea Is Healthy & No Eye Infections or Allergies & You Tried Laser Treatment But Need More Help & Advantages Over Traditional Eye Drop Treatments

The Durysta Intracameral Implant is a tiny, dissolvable device that helps lower eye pressure for people with open-angle glaucoma or high eye pressure. Instead of needing to use eye drops every day, Durysta is placed directly into the eye by our eye doctor during a quick, simple procedure. It slowly releases medicine over several months to keep eye pressure down, making it easier for patients who find daily drops hard to manage. Durysta is only given once per eye, as repeating the treatment in the same eye is not recommended. This new approach can make managing glaucoma simpler and help protect your vision for the long term.

Durysta is designed to help people lower their eye pressure without the need for daily eye drops. Not everyone can get Durysta, so our eye doctor will help decide if it is right for you.

Durysta is for adults who have open-angle glaucoma or high pressure inside their eyes (ocular hypertension). If you need to lower your eye pressure, Durysta might be a good choice.

If our eye doctor has given you bimatoprost eye drops in the past and they worked well, Durysta can give you the same results, without the daily drops.

Durysta is not safe for people with certain problems on the front part of the eye (the cornea), like corneal endothelial disease. Healthy corneas are important for this treatment.

You should not get Durysta if you have an active infection in or around your eye, or if you are allergic to bimatoprost or any part of the implant.

If you have tried laser treatment (Selective Laser Trabeculoplasty, or SLT) for glaucoma and still need to lower your eye pressure, Durysta might be a good next step.

This innovative approach not only improves the therapeutic outcome but also contributes to a better patient experience by easing the daily responsibilities involved in managing chronic conditions like glaucoma. Some of the distinct advantages of Durysta over conventional eye drop therapies include:

Enhanced Adherence & Consistent IOP Control & Reduced Medication Burden & Localized Treatment & Clinical Efficacy and Research Findings & Intraocular Pressure Reduction & Non-Inferiority to Topical Bimatoprost & Adherence and Medication Burden

Since the implant is administered once per eye, patients no longer need to remember daily drops, reducing the risk of missed doses.

The gradual and steady release of medication provides a more stable reduction in eye pressure compared to the peaks and troughs that can occur with topical treatments.

Many patients report a welcome decrease in the number of medications required after receiving their implant, which can improve overall satisfaction and ease daily stress.

By delivering bimatoprost directly to the targeted area, the implant minimizes systemic exposure and focuses treatment where it is needed most.

Durysta has been evaluated in multiple clinical trials and real-world studies, showing it can effectively lower intraocular pressure in patients with open-angle glaucoma or ocular hypertension. Research demonstrates that a single implant provides sustained pressure control and helps reduce the reliance on daily eye drops.

A single Durysta implant effectively reduces intraocular pressure (IOP) for up to 15 weeks after administration. Durysta usually lowers eye pressure for about 3 to 4 months. 

Large phase III clinical trials (ARTEMIS 1 & 2) found that Durysta was non-inferior to daily topical bimatoprost eye drops in lowering eye pressure, with similar efficacy in maintaining target IOP.

More than 70% of patients maintained adequate IOP control without needing additional medication for a full year in some studies. Durysta can reduce the need for daily eye drops for several months, but most patients will need ongoing treatment later.

Side Effect Profile & Real-World Evidence & Regulatory Status  & References & Key Features and Benefits & Sustained Release Benefits & Simplified Treatment Regimen & Targeted Action

The implant was generally well-tolerated. The most common side effect was transient eye redness. Side effects like eyelash growth and iris color change are less common with the implant than with eye drops, but can still happen.

Observational studies confirm the results seen in clinical trials, supporting Durysta as a reliable option for patients struggling with adherence to daily eye drops.

Durysta is approved by the U.S. Food and Drug Administration (FDA) for use as a single intracameral implant per eye in adults with open-angle glaucoma or ocular hypertension. This approval means that eligible patients in the United States may receive the implant as part of their glaucoma treatment plan.

  • Samuelson TW, et al. Ophthalmology. 2019.

  • Allergan. DURYSTA® Prescribing Information.

  • European Medicines Agency. Durysta Withdrawal Assessment Report.

These benefits combine to create an option that not only addresses the clinical needs of patients with glaucoma and ocular hypertension but also enhances their overall quality of life. For individuals who face challenges with eye drop adherence, Durysta offers a promising alternative that can contribute to sustained IOP management.

The localized delivery of bimatoprost via the implant provides a steady reduction in eye pressure, ensuring that the target tissues receive a consistent level of the medication. This targeted approach is one of the key reasons for the implant’s success in clinical studies. With reduced fluctuations in IOP, patients are better protected against the gradual optic nerve damage that can lead to vision loss.

Furthermore, the sustained-release mechanism minimizes the risk of compliance-related issues that often arise with daily eye drop use. For patients who have difficulty applying drops due to physical limitations or simply forgetfulness, the implant offers a reliable alternative that works in the background, ensuring continuous ocular treatment.

A single injection per eye removes the burden of daily eye drop application, enhancing adherence and treatment convenience.

Direct delivery to the ciliary body optimizes the medication’s effect on aqueous humor outflow, which is pivotal for lowering eye pressure.

If you're struggling to manage eye drops daily, consider the Durysta Intracameral Implant for glaucoma treatment. Contact Dr. [Doctor's Name] at [Practice Name] to learn more about this innovative approach to lowering eye pressure.

Reduced Systemic Exposure & Mechanism of Bimatoprost & What to Expect During the Procedure & Procedure Details & Post-Procedure Care & Practical Guidance for Considering Durysta & Comprehensive Evaluation & Personalized Treatment Plan

By localizing the effect within the eye, the implant minimizes the risk of systemic side effects often associated with other delivery methods.

Durysta contains bimatoprost, which helps lower eye pressure by increasing the outflow of fluid from the eye through two natural drainage pathways. By improving drainage efficiency, the medication effectively lowers the intraocular pressure that characterizes open-angle glaucoma and ocular hypertension.

The Durysta implant is administered by our eye doctor using precise, minimally invasive techniques. During the procedure, the implant is placed into the anterior chamber of the eye via a single-use 28‑gauge applicator. This quick, efficient process minimizes patient discomfort and reduces office time.

Following the injection, patients are advised to remain upright for at least one hour to ensure the implant settles correctly within the eye. This post‑procedure recommendation is part of the comprehensive care our eye doctor provide to support optimal implant performance. Patients generally appreciate the convenience of a one‑time procedure that replaces daily treatment routines, making Durysta an attractive option for those who struggle to maintain a regular eye‑drop schedule.

This structured approach not only simplifies the decision-making process but also provides reassurance that every aspect of your eye health is being carefully considered and monitored. If you have any doubts or questions, scheduling an appointment with our eye doctor is the next best step to receiving personalized guidance. If you are evaluating your treatment options for managing elevated eye pressure, consider discussing the Durysta Intracameral Implant with our eye doctor. Here’s a practical approach to help determine if Durysta is appropriate for you:

A detailed assessment of your intraocular pressure, corneal health, and overall ocular condition is essential. This evaluation will help determine whether you are an ideal candidate for the implant.

Based on your specific condition, our eye doctor will develop a personalized treatment plan that may include Durysta as a solution for sustained IOP reduction.

Discussion of Benefits and Risks & Long-Term Monitoring & Can I have more than one Durysta implant per eye? & Will I need to take eye drops after the implant? & How will I know if the implant is working? & What should I do if I miss a follow-up appointment? & Are there any signs I should watch for after the procedure? & Is Durysta safe during pregnancy or breastfeeding?

It is vital to have an open conversation about the expected outcomes and potential side effects of Durysta. Our eye doctor will help you understand the balance between improved adherence and the rare risks associated with the implant.

Even with a single administration, periodic follow-ups are crucial to ensure that your eye pressure remains controlled and that your eye health is maintained over time.

No, Durysta can only be given once in each eye. Repeat implantation in the same eye is not allowed due to the risk of permanent corneal damage.

Many patients can reduce or stop their daily eye drops for several months after receiving Durysta. However, most people will eventually need further treatment, which may include restarting eye drops or trying other options.

Our eye doctor will monitor your eye pressure during follow-up visits. If the pressure is well controlled and you don’t have symptoms like blurred vision or pain, the implant is working as intended.

It’s important to attend all scheduled follow-ups. If you miss an appointment, contact your eye clinic as soon as possible to reschedule so your doctor can check your eye pressure and overall eye health.

Contact your doctor right away if you experience severe pain, sudden vision changes, increased redness, sensitivity to light, or any signs of infection.

The safety of Durysta during pregnancy or breastfeeding is not known. If you are pregnant, planning to become pregnant, or breastfeeding, inform your doctor before receiving the implant.

Durysta Intracameral Implant for Glaucoma Management

If you're struggling to manage eye drops daily, consider the Durysta Intracameral Implant for glaucoma treatment. Contact Dr. [Doctor's Name] at [Practice Name] to learn more about this innovative approach to lowering eye pressure.

Common Questions

Durysta can only be administered once per eye. Repeating the treatment in the same eye increases the risk of corneal damage.
Many patients can reduce or stop eye drops for several months after the implant. However, ongoing monitoring is necessary as most will need further treatment eventually.
Your eye doctor will regularly monitor your eye pressure. If it remains controlled without symptoms, the implant is likely effective.
It’s crucial to attend all follow-up appointments. Reschedule immediately if you miss one to ensure your eye health is monitored appropriately.
Watch for severe pain, sudden vision changes, increased redness, or sensitivity to light, and contact your doctor if these occur.
The safety of Durysta during pregnancy or breastfeeding is not well-established, so consult your doctor before receiving the implant if you're pregnant or breastfeeding.
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Durysta Intracameral Implant for Glaucoma Management

Manage glaucoma effectively with the Durysta Intracameral Implant. Find top optometrists near you through Specialty Vision.

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