InflammaDry: Rapid Test for Dry Eye Disease and Ocular Inflammation

InflammaDry is revolutionizing the diagnosis of dry eye disease by rapidly detecting MMP-9 levels and identifying ocular inflammation. This non-invasive test enables eye care professionals to make informed treatment decisions quickly.

Table of Contents

Introduction

InflammaDry is a rapid, in-office diagnostic test designed to detect elevated levels of an inflammatory marker known as MMP-9 in the tears of patients with dry eye disease. This non-invasive test provides eye care professionals with vital information about inflammation on the ocular surface within minutes. By accurately identifying inflammation, InflammaDry guides treatment decisions that can improve patient outcomes and preserve long-term eye health.

What Is InflammaDry?

InflammaDry is the first and only rapid, CLIA-waived test performed right in the office to help diagnose dry eye disease by detecting the presence of matrix metalloproteinase-9 (MMP-9) in tear samples. Unlike traditional tests that only evaluate tear production or stability, InflammaDry specifically identifies ocular surface inflammation as a key factor in dry eye. This simple, disposable test is designed to be both efficient and cost-effective, making it a valuable tool for modern eye care.

The Science Behind InflammaDry

Understanding MMP-9 and Its Role in Dry Eye Disease

MMP-9 is an enzyme that plays a significant role in the breakdown of extracellular matrix proteins, and its elevated levels in tears are a strong indicator of inflammation on the ocular surface. In dry eye disease, changes in tear film composition and ocular inflammation can lead to a cascade of events that result in discomfort, redness, and tissue damage. By measuring the level of MMP-9, eye doctors can better understand the inflammatory status of the eye and decide whether a patient’s dry eye is primarily driven by inflammation or other factors.

This targeted approach is crucial because inflammation often appears before clinical signs of dry eye become apparent, allowing for earlier intervention. Recognizing elevated MMP-9 levels can be the first step toward a treatment plan designed to reduce inflammation, protect the ocular surface, and enhance overall visual comfort.

Find a top optometrist near you who utilizes InflammaDry to enhance your dry eye treatment and improve your quality of life.

How InflammaDry Works

The Testing Process: Simple, Quick, and Painless

The InflammaDry test is performed using a direct sampling microfiltration technology that collects a tear sample from the inside lining of the lower eyelid. Here’s a brief overview of the process:

  • Tear Collection: A small, soft piece of fabric gently dabs the lower eyelid to collect a sufficient tear sample. This step is quick and completely non-invasive.
  • Activation Process: The collected sample is then mixed with a buffer solution that activates the test reagents.
  • Incubation: Within approximately 10 minutes, the test yields a result by displaying a color change on the test device.
  • Result Interpretation: A solitary blue line indicates a negative result (normal levels of MMP-9), while a blue line accompanied by a red line signifies a positive result (elevated MMP-9 levels and thus inflammation).

This entire procedure is completed in about 10 minutes, enabling eye care professionals to quickly discuss results and treatment recommendations with the patient before they leave the office.

Benefits of InflammaDry

There are several reasons why InflammaDry has become a game-changer in the diagnosis and management of dry eye disease:

  • Rapid Results: The test provides results in as little as 10 minutes, allowing for immediate decision-making.
  • Ease of Use: With its simple, four-step process, the test can be easily performed by trained technicians in the office.
  • Non-Invasive and Comfortable: The tear collection method is painless and does not require any complex procedures or specialized equipment.
  • High Accuracy: InflammaDry has been shown to have high sensitivity and specificity—studies report figures around 85% sensitivity and 94% specificity. These numbers mean that the test reliably detects inflammation when it is present and correctly identifies cases where inflammation is not elevated.
  • Cost-Effective: Being a disposable and low-cost test, InflammaDry minimizes the need for additional equipment or expensive diagnostic tools.

InflammaDry: Rapid Test for Dry Eye Disease and Ocular Inflammation

Find a top optometrist near you who utilizes InflammaDry to enhance your dry eye treatment and improve your quality of life.

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InflammaDry: Rapid Test for Dry Eye Disease and Ocular Inflammation

InflammaDry is a fast, accurate test that detects MMP-9 levels to help diagnose dry eye disease and guide treatment decisions.

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