While the current data and research do not show definitive evidence of a genetic component to keratoconus, studies suggest that genetic and family history may be a risk factor in this degenerative eye disorder.
Keratoconus manifests with the following symptoms:
While vision may be easily corrected during the early onset of this complication with standard glasses and corrective lenses, as the severity of the condition increases and the aforementioned signs worsen, the patient may develop astigmatism or nearsightedness.
In advanced cases certain treatments such as contact lenses and cornea cross-linking to strengthen collagen fibers, may no longer be viable options. Sometimes a patient may require scleral lenses post corneal transplantation.
People with the following genetic conditions may be predisposed for keratoconus:
When considering the above-mentioned conditions and possible connections with keratoconus, it is important to note that several involve complications that may lead to excessive eye-rubbing, which in turn may damage the cornea and cause this condition.
Furthermore, people with Downs Syndrome may be more apt to engage in injurious eye-rubbing and depending on the severity of their condition, they may be less capable of communicating discomfort.
There may be a hereditary component to this condition. Studies show that approximately 1 in 10 people with keratoconus have a parent with this disorder.
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