Minimally Invasive Glaucoma Surgery (MIGS) for Effective Glaucoma Management

Minimally Invasive Glaucoma Surgery (MIGS) offers a modern approach to glaucoma management, focusing on lowering eye pressure with minimal recovery time. Discover how MIGS can enhance your eye health.

Table of Contents

Understanding MIGS and Its Significance

Glaucoma is the leading cause of irreversible vision loss, and controlling intraocular pressure (IOP) is crucial for preserving your sight. Our glaucoma specialists have increasingly turned to MIGS to help bridge the treatment gap for patients whose IOP remains elevated despite eye drops or laser therapy. MIGS procedures are tailored to improve drainage through the eye’s natural systems while reducing reliance on medications.

Defining the MIGS Procedure

MIGS procedures are distinguished by a set of core characteristics that make them less disruptive than traditional surgery. They offer a high safety profile with much lower risks of complications such as hypotony, choroidal hemorrhage, and infection. By preserving the normal anatomy of the eye through small incisions and a specialized approach to reduce pressure by enabling a more natural restoration of fluid drainage.

In essence, MIGS focuses on achieving meaningful reductions in IOP—typically around a 20% drop—with minimal surgical trauma. This category of surgery is broadly divided by the mechanism used to facilitate aqueous outflow or reduce the production of fluid in the eye.

How MIGS Works: Restoring the Eye’s Natural Drainage

Minimally Invasive Glaucoma Surgery (MIGS) is designed to lower eye pressure by improving how fluid drains from the eye. In glaucoma, high intraocular pressure (IOP) occurs when the eye’s natural drainage system doesn’t work efficiently, leading to potential damage to the optic nerve. MIGS procedures help relieve this pressure in a way that is safer and less invasive than traditional glaucoma surgeries.

Unlike older surgical techniques that create entirely new drainage systems, MIGS works by enhancing or modifying the eye’s existing drainage structures. The goal is to either improve the flow of aqueous humor (the fluid inside the eye) through natural pathways or, in some cases, reduce the amount of fluid the eye produces.

Enhancing the Trabecular Meshwork

The trabecular meshwork is a spongy tissue that helps drain fluid from the eye into Schlemm’s canal, which then carries the fluid out of the eye. In glaucoma, this area can become blocked or resistant to fluid movement, raising eye pressure. MIGS procedures can improve this function by:

  • Using trabecular bypass stents: Tiny stents (such as the iStent or Hydrus Microstent) are placed inside the trabecular meshwork to create a direct pathway for fluid to flow more easily into Schlemm’s canal.
  • Removing obstructive tissue: Procedures like goniotomy or trabeculotomy remove tiny portions of the trabecular meshwork that may be restricting fluid outflow.

Widening Schlemm’s Canal with Viscodilation or Canaloplasty

Schlemm’s canal is a circular drainage channel in the eye that helps carry fluid out of the trabecular meshwork and into the bloodstream. Some MIGS procedures focus on expanding this canal to enhance drainage, including:

  • Microcatheter-assisted dilation: A tiny catheter is inserted into Schlemm’s canal to gently stretch and widen it, improving fluid drainage.
  • Canaloplasty: This procedure involves inserting a small device that applies viscoelastic gel to keep Schlemm’s canal open, allowing for better outflow of fluid.

Creating a New Drainage Pathway

When the eye’s natural drainage system is too impaired to function properly, some MIGS devices create alternative routes for fluid to exit the eye. These include:

  • Subconjunctival drainage: Some MIGS procedures, like the Xen Gel Stent, create a small channel that directs fluid into the subconjunctival space (a layer under the outer surface of the eye), where it can be absorbed naturally.
  • Suprachoroidal drainage: Certain devices allow fluid to drain into the suprachoroidal space, another natural area within the eye that can help regulate pressure.

Reducing Fluid Production

Instead of improving drainage, some MIGS procedures focus on reducing the amount of fluid the eye produces. One technique, called endocyclophotocoagulation (ECP), uses a laser to treat the ciliary body—the part of the eye responsible for fluid production. By gently reducing its activity, the eye produces less fluid, helping to lower pressure.

Take the first step towards better eye health. Find a top optometrist or ophthalmologist near you who specializes in MIGS today!

Exploring MIGS Options: Devices and Surgical Techniques

Trabecular Meshwork Bypass Devices

The trabecular meshwork is the primary site of resistance within the eye’s drainage system. MIGS devices that target this area help create a direct pathway for fluid to flow into Schlemm’s canal. Two key examples include:

  • iStent and iStent Inject: These are tiny, titanium microdevices designed to bypass the trabecular meshwork. The iStent procedures typically offer a meaningful reduction in IOP when implanted with cataract surgery. Studies show that many patients achieve an IOP reduction of around 20% or experience a significant drop in eye drop dependence.
  • Hydrus Microstent: Made of a flexible nitinol alloy, the Hydrus device both bypasses the trabecular meshwork and scaffolds Schlemm’s canal to maintain its openness. It is also often implanted during cataract surgery and works well in patients with mild to moderate glaucoma.

Trabecular Meshwork Excision Techniques

In addition to stents, there are surgical approaches that remove or excise portions of the trabecular meshwork to create a larger drainage opening. These procedures have the advantage of not leaving behind an implant, which can be beneficial in preserving the eye’s anatomy for the future.

  • Kahook Dual Blade (KDB) Goniotomy: This specialized blade is designed to precisely excise part of the trabecular meshwork. The dual-blade system creates paired incisions, reducing the risk of residual tissue scarring that could impede fluid flow.
  • Trabectome: This surgical system uses electrocautery to remove a strip of the trabecular meshwork along with the inner wall of Schlemm’s canal. The continuous irrigation and aspiration system keeps the operative area clear, aiding in a smooth surgical process and reliable outcomes.
  • Gonioscopy Assisted Transluminal Trabeculotomy (GATT): A technique that involves making a 360-degree incision of the trabecular meshwork using either a microcatheter or a 4-0 nylon suture. GATT is effective in achieving a circumferential opening, which can be particularly useful in patients who have not responded to other treatments.

Cannulation and Viscodilation Procedures

Some MIGS approaches focus on enhancing the natural canal structure itself, without major tissue cutting. These procedures involve cannulating Schlemm’s canal, followed by the controlled injection of viscoelastic material to expand the canal and distal collector channels.

  • VISCO360/OMNI System: This device enables both the viscodilation of the canal and a trabeculotomy to increase outflow facility. By gently dilating Schlemm’s canal, the procedure improves the eye’s natural drainage while reducing stress on the tissues.
  • Ab Interno Canaloplasty (ABiC): Using a microcatheter with light guidance, ABiC involves threading through Schlemm’s canal with a controlled viscodilation on withdrawal. This procedure enhances fluid drainage without destroying the native anatomy, a quality that appeals to many patients and surgeons alike.

Suprachoroidal and Subconjunctival Shunts

For some patients, bypassing the conventional drainage system may be preferable. These techniques redirect aqueous humor to spaces outside the natural drainage pathway:

  • XEN Gel Stent: Although its classification as a MIGS can be a subject of debate, this gel stent is used to shunt fluid from the anterior chamber into the subconjunctival space. It is especially useful for patients with refractory glaucoma who have not responded well to other treatments.
  • Suprachoroidal Approaches: Although the CyPass microstent once provided this route by creating a controlled cleft into the suprachoroidal space, it has been withdrawn from the market. However, research and innovation continue in this area, exploring methods to safely leverage the uveoscleral outflow pathway.

Reducing Aqueous Production: Ciliary Body Ablation

Another method to lower intraocular pressure is by reducing the production of aqueous humor. Instead of enhancing drainage, these procedures target the part of the eye responsible for fluid production:

  • Endocyclophotocoagulation (ECP): This procedure uses a laser probe inserted through a small corneal incision to directly visualize and ablate areas of the ciliary body. By reducing fluid production, ECP can provide a significant drop in IOP, making it a valuable tool in the management of multiple forms of glaucoma.

Who Benefits Most from MIGS?

When our glaucoma specialists evaluate candidates for MIGS, they look closely at the severity of glaucoma and the individual’s eye anatomy. MIGS is particularly beneficial for patients with mild to moderate glaucoma who have either not found relief with medications or struggle with compliance. Those undergoing cataract surgery may also experience additional benefits when MIGS is performed concurrently.

Ideal candidates typically include:

  • Patients with primary open-angle glaucoma who need a modest reduction in IOP.
  • Individuals who are intolerant of or have difficulty adhering to long-term eye drop regimens.
  • Patients with mild to moderate glaucoma looking for a safer alternative to traditional incisional surgery.

However, in cases where glaucoma is more advanced and achieving a very low IOP is critical, traditional incisional surgeries might still be recommended. Our glaucoma specialists work closely with each patient to tailor the treatment strategy to their unique needs and ensure optimal safety and effectiveness.

Minimally Invasive Glaucoma Surgery (MIGS) for Effective Glaucoma Management

Take the first step towards better eye health. Find a top optometrist or ophthalmologist near you who specializes in MIGS today!

Common Questions

No, MIGS and laser glaucoma surgery are different treatments. MIGS involves tiny devices or surgical techniques, while laser surgery uses energy to improve drainage.
MIGS does not cure glaucoma. It slows progression by lowering eye pressure, requiring ongoing monitoring and possible additional treatments.
Results can vary but many patients enjoy significant IOP reductions for several years. Regular follow-ups are essential for effective ongoing management.
Regular follow-up visits are crucial to monitor IOP and adjust medications if needed. Some patients may reduce or stop their medications.
MIGS is suitable for patients with mild to moderate open-angle glaucoma, especially those not achieving desired IOP reduction with medications or patients undergoing cataract surgery.
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Minimally Invasive Glaucoma Surgery (MIGS) for Effective Glaucoma Management

Enhance your eye health with Minimally Invasive Glaucoma Surgery (MIGS) to effectively manage eye pressure and preserve vision.

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